Liver disease for Charlson index (primary care)
Name liver_charlson_gprd
Chapter Digestive system diseases/Liver disease
Definition
Acording to Charlson, mild liver disease includes patients with cirrhosis but no portal hypertension or variceal bleeding. We also exclude codes for 'sequelae' of liver disease or chronic autommune or viral hepatitis (unless they mention cirrhosis).

'Severe liver disease' includes codes for cirrhosis and portal hypertension, oesophageal varices or
liver failure. We assume that it does not include acute hepatic failure. The ICD-10 list of Sundararajan et al. includes only K729, K766, K767, K721, i.e. hepatic failure (unspecified) portal hypertension, varices and hepatorenal syndrome. Hepatic encephalopathy is included in hepatic failure in ICD-10 and does not have a specific code.
Data Type Categorical
Data sources GPRD
Repeated Yes
Valid event date range 01/01/1900 - 25/03/2010
Agreed 06 Jan 2012 (Revision 1)
Category Definition
3 Mild liver disease
4 Severe liver disease
Implementation
Category assigned according to codelist.
Codelist version1
Codelist authorsAnoop Shah
Creation date06 Jan 2012
Category (code) Clinical code Clinical term Datasource lookup
Mild liver disease (3) C310400 Glycogenosis with hepatic cirrhosis 19512
Mild liver disease (3) C350012 Pigmentary cirrhosis of liver 8206
Mild liver disease (3) J61..00 Cirrhosis and chronic liver disease 6863
Mild liver disease (3) J612.00 Alcoholic cirrhosis of liver 4743
Mild liver disease (3) J612.11 Florid cirrhosis 68376
Mild liver disease (3) J614.00 Chronic hepatitis 1754
Mild liver disease (3) J614000 Chronic persistent hepatitis 23578
Mild liver disease (3) J614100 Chronic active hepatitis 9029
Mild liver disease (3) J614200 Chronic aggressive hepatitis 1755
Mild liver disease (3) J614400 Chronic lobular hepatitis 66534
Mild liver disease (3) J614y00 Chronic hepatitis unspecified 53877
Mild liver disease (3) J614z00 Chronic hepatitis NOS 15489
Mild liver disease (3) J615.00 Cirrhosis - non alcoholic 16725
Mild liver disease (3) J615.11 Portal cirrhosis 47257
Mild liver disease (3) J615100 Multilobular portal cirrhosis 69204
Mild liver disease (3) J615300 Diffuse nodular cirrhosis 3450
Mild liver disease (3) J615400 Fatty portal cirrhosis 44676
Mild liver disease (3) J615500 Hypertrophic portal cirrhosis 92909
Mild liver disease (3) J615600 Capsular portal cirrhosis 40567
Mild liver disease (3) J615700 Cardiac portal cirrhosis 27438
Mild liver disease (3) J615800 Juvenile portal cirrhosis 96664
Mild liver disease (3) J615812 Indian childhood cirrhosis 58184
Mild liver disease (3) J615D00 Bacterial portal cirrhosis 73482
Mild liver disease (3) J615H00 Infectious cirrhosis NOS 48928
Mild liver disease (3) J615y00 Portal cirrhosis unspecified 55454
Mild liver disease (3) J615z00 Non-alcoholic cirrhosis NOS 16455
Mild liver disease (3) J615z11 Macronodular cirrhosis of liver 22841
Mild liver disease (3) J615z12 Cryptogenic cirrhosis of liver 18739
Mild liver disease (3) J615z13 Cirrhosis of liver NOS 1638
Mild liver disease (3) J616.00 Biliary cirrhosis 9494
Mild liver disease (3) J616000 Primary biliary cirrhosis 5638
Mild liver disease (3) J616100 Secondary biliary cirrhosis 15424
Mild liver disease (3) J616200 Biliary cirrhosis of children 91591
Mild liver disease (3) J616z00 Biliary cirrhosis NOS 58630
Mild liver disease (3) J617000 Chronic alcoholic hepatitis 7602
Mild liver disease (3) J61y300 Portal fibrosis without cirrhosis 40963
Mild liver disease (3) J635600 Toxic liver disease with fibrosis and cirrhosis of liver 44120
Mild liver disease (3) Jyu7100 [X]Other and unspecified cirrhosis of liver 6015
Severe liver disease (4) 7609.00 Open operations on oesophageal varices 24220
Severe liver disease (4) 7609300 Local ligation of oesophageal varices 43404
Severe liver disease (4) 7609400 Open injection sclerotherapy to oesophageal varices 20912
Severe liver disease (4) 7609z00 Open operation on oesophageal varices NOS 20233
Severe liver disease (4) 760C500 Fibreoptic endoscopic banding of oesophageal varices 16759
Severe liver disease (4) 760F300 Rigid oesophagoscopic injection sclerotherapy oesoph varices 47214
Severe liver disease (4) 760F400 Rigid oesophagoscopic banding of oesophageal varices 46647
Severe liver disease (4) G85..11 Oesophageal varices 1641
Severe liver disease (4) G850.00 Oesophageal varices with bleeding 24989
Severe liver disease (4) G851.00 Oesophageal varices without bleeding 30655
Severe liver disease (4) G852.00 Oesophageal varices in diseases EC 44424
Severe liver disease (4) G852000 Oesophageal varices with bleeding in diseases EC 96756
Severe liver disease (4) G852100 Oesophageal varices without bleeding in diseases EC 73139
Severe liver disease (4) G852200 Oesophageal varices in cirrhosis of the liver 26319
Severe liver disease (4) G852300 Oesophageal varices in alcoholic cirrhosis of the liver 8363
Severe liver disease (4) G852z00 Oesophageal varices in diseases EC NOS 62582
Severe liver disease (4) G858.00 Oesophageal varices NOS 10797
Severe liver disease (4) J622.00 Hepatic coma 23511
Severe liver disease (4) J622.11 Encephalopathy - hepatic 22411
Severe liver disease (4) J623.00 Portal hypertension 5129
Severe liver disease (4) J624.00 Hepatorenal syndrome 10636
Severe liver disease (4) J625.00 [X] Hepatic failure 24901
Severe liver disease (4) J625.11 [X] Liver failure 21769
Severe liver disease (4) J62y.11 Hepatic failure NOS 56070
Severe liver disease (4) J62y.12 Liver failure NOS 23775
Severe liver disease (4) J62y.13 Hepatic failure 16062
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