Estimated glomerular filtration rate (CKD-EPI formula)
Name egfr_ckdepi_gprd
Chapter Genitourinary system diseases/Renal failure
Definition
Estimated glomerular filtration rate using CKD-EPI formula, using serum creatinine in micromol/L.

Reference: Levey AS et al. A New Equation to Estimate Glomerular Filtration Rate, Ann Intern Med. 2009;150:604-612. http://annals.org/article.aspx?articleid=744469

Note: We do not know if creatinine measurements in CPRD are calibrated to IDMS. Therefore we multiply the raw creatinine by 0.95 to obtain conservative values for perhaps uncalibrated creatinine. We also multiply by 0.011312 to convert from micromol/L to mg/dL.
Data Type Continuous
Data sources GPRD
Repeated Yes
Units ml/min
Valid event date range 01/01/1900 - 25/03/2010
Agreed 08/11/2012 (Revision 1)
Implementation
egfr_ckdepi = 141 * min(crea_gprd * 0.010746 / K, 1)^alpha
* max(crea_gprd * 0.010746 / K, 1)^-1.209 
* 0.993^age * 1.018 [if female]  * 1.159 [if black]

where:
alpha = -0.329 for females, -0.411 for males
K = 0.7 for females, 0.9 for males
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